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KMID : 1189420160290010033
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2016 Volume.29 No. 1 p.33 ~ p.46
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Anti-atopic Effect of Chamaecyparis Obtusa oil (CHO_O) in DNCB-induced atopic dermatitis-like skin lesions NC/Nga mice
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Son Gi-Jung
Park Jung-Hwan
Kim Yoon-Ha
Go Ga-Yeon
Kim Yun-Joo
Han Ji-Yeon
Ko Ki-Tae
Ahn Taek-Won
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Abstract
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Objective : The aim of this study is to investigate the effect of Chamaecyparis Obtusa Oil to NC/Nga mice induced in Atopic dermatitis-like skin lesions by DNCB Mthods.
Methods : NC/Nga mice which have been induced to Atopic dermatitis-like skin lesions by DNCB are divided into 3 groups, the one is the mice which have been spread with Chamaecyparis Obtusa Oil 2% cream, the other is which have been spread with dexamethasone (Dexa.) 0.5% on their Atopic lesion, another is the control group. then we take the blood sample of each group to measure state of the dorsal skin, the number of immunocytes. and resect the skin lesion to analyze the state of cells.
Result & Conclusion : There are meaningful results of measuring the number of IgE, IL-4, IFN-γ and the state of the skin lesion and cells in the group with hamaecyparis Obtusa Oil 2% cream in comparison with the other groups.
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KEYWORD
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Anti-atopic, Chamaecyparis Obtusa, atopic dermatitis
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